Recombinant Actin anticorps

N° du produit ABIN7543295

Cet anticorps Lapin Chimeric détecte spécifiquement Actin dans ELISA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant Actin anticorps (ABIN7543295)

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp Actin est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G8C7A6

Détail du produit anti-Actin anticorps

Fonction: Anti-Alpha actin 1 [3G8C7A6], Rabbit IgG, kappa

Specificité: This antibody binds actin. Actin is a type of spherical multi-functional protein that forms a microfilament. Actin is widely existent in eukaryotic organisms, and there is a major component constituting the muscle segment and the cell skeleton in the cytoplasm and cellular nucleus of the intramuscular cell. Muscle specific actin (MSA) is a highly conserved, ubiquitous protein found in muscle and some non-muscle cells. In addition to participating in the normal morphology of maintaining cells, actin also participates in the formation, adhesion, migration, apoptosis, material transport, transmembrane information transfer, and receptor aggregation.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing BALB/c mice with a recombinant human actin protein.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody is highly similar to the commercially available anti-actin antibody HHF35. This antibody can use used in the immunohistochemical staining of smooth fibroids. This antibody can be used in the identification of actin from various tissues including brain, heart, cerebellum, esophageal, adrenal, stomach, ovaries, small intestines, pancreatic, colorectal, parathyroid, liver, pituitary, salivary gland, testicular, kidney, thyroid, prostate, breast, uterus, spleen, bladder, tonsil, skeletal muscle, thymus (young children), skin, bone marrow, peripheral nerve, lung, melodder cells. The binding specificity of this antibody towards actin was determined using ELISA. The original IgG2b antibody binds actin with an affinity constant of 6.26X10^9 M^(-1) (CN113817055).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Actin

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Autre désignation: Alpha actin 1

Sujet: Actin, ACTA1, ACTA, Actin alpha skeletal muscle, Alpha-actin-1, Muscle specific actin, MSA, HHF35, CGMCNO.22312, HHF35

UniProt: P68133

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development